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    Covid-19 vaccine that could soon be rolled out to Australians is found to be ‘90% effective’

    Covid-19 vaccine that could soon be rolled out to Australians is found to be ’90 per cent effective at preventing the virus’

    Australia has welcomed news that a COVID-19 vaccine that’s been developed is 90 per cent effective based on early test results.

    The federal government has ordered 10 million doses of the Pfizer and BioNTech vaccine, which has exceeded the US manufacturer’s expectations. 

    Pfizer’s announcement came less than a week after a US election seen as a referendum on President Donald Trump´s handling of the scourge, which has killed more than 1.2 million people worldwide, including more than 800 Australians.

     ‘The data on our vaccine candidates continues to be positive. We will examine the evidence carefully but the latest results are heartening news,’ health minister Greg Hunt told News Corp.

    ‘We´re in a position potentially to be able to offer some hope,’ Dr Bill Gruber, Pfizer´s senior vice president of clinical development told The Associated Press. 

    ‘We´re very encouraged.’

    Pfizer, which is developing the vaccine with its German partner BioNTech, now is on track to apply later this month for emergency-use approval from the U.S. Food and Drug Administration, once it has the necessary safety information in hand.

    Even if all goes well, authorities have stressed it is unlikely any vaccine will arrive much before the end of the year, and the limited initial supplies will be rationed.

    Pfizer, which developed the vaccine with German drugmaker BioNTech, are the first to release successful data from an interim analysis of a large-scale clinical trial 

    Dr. Anthony Fauci, the U.S. government’s top-infectious disease expert, said the results suggesting 90% effectiveness are ‘just extraordinary,’ adding: ‘Not very many people expected it would be as high as that. 

    ‘It´s going to have a major impact on everything we do with respect to COVID,’ Fauci said as Pfizer appeared to take the lead in the all-out global race by pharmaceutical companies and various countries to develop a well-tested vaccine against the virus.

    Dr. Bruce Aylward, the World Health Organization´s senior adviser, said Pfizer’s vaccine could ‘fundamentally change the direction of this crisis’ by March, when the U.N. agency hopes to start vaccinating high-risk groups.

    Global markets, already buoyed by the victory of President-elect Joe Biden, rocketed on the news from Pfizer. The S&P 500 was up 3.3% in afternoon trading, while the Dow Jones Industrial Average gained more than 1,300 points. Pfizer jumped more than 11%. Other vaccine stocks were up as well.

    However, the announcement doesn’t mean for certain that a vaccine is imminent: This interim analysis, from an independent data monitoring board, looked at 94 infections recorded so far in a study that has enrolled nearly 44,000 people in the U.S. and five other countries.

    Some participants got the vaccine, while others got dummy shots. Pfizer released no specific breakdowns, but for the vaccine to be 90% effective, nearly all the infections must have occurred in placebo recipients. The study is continuing, and Pfizer cautioned that the protection rate might change as more COVID-19 cases are added to the calculations.

    Dr. Jesse Goodman of Georgetown University, former chief of the FDA´s vaccine division, called the partial results ‘extremely promising’ but ticked off many questions still to be answered, including how long the vaccine´s effects last and whether it protects older people as well as younger ones.

    Trump, who had suggested repeatedly during the presidential campaign that a vaccine could be ready by Election Day, tweeted: ‘STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!’

    Biden, for his part, welcomed the news but cautioned that it could be many months before vaccinations become widespread in the U.S., and he warned Americans to rely on masks and social distancing in the meantime. He said the country still faces a ‘dark winter.’

    Confirmed infections in the U.S. eclipsed 10 million on Monday, the highest in the world. New cases are running at all-time highs of more than 100,000 per day. And tens of thousands more deaths are feared in the coming months, with the onset of cold weather and the holidays.

    Pfizer´s vaccine is among four candidates already in huge studies in the U.S., with still more being tested in other countries. Another U.S. company, Moderna Inc., also hopes to file an application with the FDA late this month.

    Both companies’ shots are made with a brand-new technology. These ‘mRNA vaccines’ aren’t made with the coronavirus itself, meaning there’s no chance anyone could catch it from the shots. Instead, the vaccine contains a piece of genetic code that trains the immune system to recognize the spiked protein on the surface of the virus.

    The timing of Pfizer’s announcement is likely to feed unsubstantiated suspicions from Trump supporters that the pharmaceutical industry was withholding the news until after the election. Donald Trump Jr. tweeted: ‘The timing of this is pretty amazing. Nothing nefarious about the timing of this at all right?’

    Pfizer has insisted that its work is not influenced by politics and that it was ‘moving at the speed of science.’ Its independent data monitors met on Sunday, analyzing the COVID-19 test results so far and notifying Pfizer.

    Pfizer opted not to join the Trump administration´s Operation Warp Speed, which helped fund a half-dozen vaccine makers. The company instead said it has invested billions of its own dollars.

    The strong results were a surprise. Scientists have warned for months that any COVID-19 shot may be only as good as flu vaccines, which are about 50% effective and require yearly immunizations. Earlier this year, Fauci said he would be happy with a COVID-19 vaccine that was 60% effective.

    Whatever the ultimate level of protection, no one knows if people will need regular vaccinations.

    Also, volunteers in the study received a coronavirus test only if they developed symptoms, leaving unanswered whether vaccinated people could get infected but show no symptoms and unknowingly spread the virus.

    Pfizer has estimated it could have 50 million doses available globally by the end of 2020, enough for 25 million people.

    Public Citizen, the consumer advocacy group, called the release of the preliminary and incomplete data ‘bad science’ and said that any enthusiasm over the results ‘must be tempered’ until they are reviewed by the FDA and its independent experts.

    ‘Crucial information absent from the companies´ announcement is any evidence that the vaccine prevents serious COVID-19 cases or reduces hospitalizations and deaths due to the disease,’ the organization said.


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